Conference Abstract | Volume 8, Abstract ELIC2025167 (Poster 118) | Published: 06 Aug 2025

A systematic review and meta-analysis of machine learning-based early warning systems for Lassa fever outbreaks in West Africa

Olaiya Paul Abiodun1, Folake  Abiola Abiodun-Omogoye2

1Texila American University, Zambia and GY Campus, 2Funmilayo ARETE Charity Healthcare Initiative (FACHI), Abuja, Nigeria

&Corresponding author: Folake Abiola Abiodun-Omogoye, Funmilayo ARETE Charity Healthcare Initiative (FACHI), Abuja, Nigeria. Email: countrydirector@areteconsortiumconnect.org

Received: 01 Jul 2025, Accepted: 09 Jul 2025, Published: 06 Aug 2025

Domain: Infectious Disease Epidemiology

This is part of the Proceedings of the ECOWAS 2nd Lassa fever International Conference in Abidjan, September 8 – 11, 2025

Keywords: Lassa fever, artificial intelligence, machine learning, surveillance, West Africa, systematic review, and meta-analysis

©Folake Abiola Abiodun-Omogoye et al. Journal of Interventional Epidemiology and Public Health (ISSN: 2664-2824). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Folake Abiola Abiodun-Omogoye et al., A systematic review and meta-analysis of machine learning-based early warning systems for Lassa fever outbreaks in West Africa. Journal of Interventional Epidemiology and Public Health. 2025;8(ConfProc5):00262. https://doi.org/10.37432/jieph-confpro5-00262

Introduction

Lassa fever is still a big public health problem in West Africa, and outbreaks happen again and again in many countries in the region. This systematic review and meta-analysis looked at how well artificial intelligence and machine learning can help West African countries keep an eye on Lassa fever and predict outbreaks. 

Methods

We searched the PubMed, Scopus, and African Journals Online databases (2015-2025) in a systematic way for studies that used machine learning algorithms to track Lassa fever. We used random-effects models to do a meta-analysis on 24 eligible studies to see how well different Al models could predict outcomes. 

Results

The analysis looked at 24 studies from Nigeria (12), Sierra Leone (5), Liberia (4), and three other West African countries. For finding outbreaks, random forest algorithms had the best predictive accuracy (pooled AUC = 0.89, 95% Cl: 0.85-0.93), followed by deep learning models (pooled AUC = 0.85, 95% Cl: 0.81-0.89). Adding climate data, rodent surveillance, and human case reports to the model made it work 27% better (p< 0.001). Compared to traditional surveillance methods, real-time data processing systems cut the time it took to find an outbreak by 8.3 days (95% Cl: 6.2-10.4). 

Conclusion

Surveillance systems that use machine learning are showing good results in finding and predicting Lassa fever outbreaks in West Africa. Combining data from different sources and using automated analysis makes it much easier to find outbreaks quickly. These results support the use of Al-powered surveillance systems to improve the ability of regions to prepare for and respond to Lassa fever outbreaks. Future studies should concentrate on making data collection methods more consistent and building stronger cross-border surveillance networks.

 

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Keywords

  • Lassa fever
  • Artificial intelligence
  • Machine learning
  • Surveillance
  • West Africa
  • Systematic review
  • Meta-analysis
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