Conference Abstract | Volume 8, Abstract ELIC202569 (Poster 129) | Published:  06 Aug 2025

Factors associated with COVID-19 vaccine compliance and reasons for hesitancy among adults in Benin: A cross-sectional survey,

Damien Barikissou Georgia1,&, Vlavonou Melkisédek1, Houénou Joseph1, Noumavo Dieudonné1, Sonounameto Roland Christel2, Ouendo Edgard Marius3, Aguemon Badirou4

1Population and Health Research Centre, University of Abomey-Calavi, Benin Republic, 2The Laboratoire de Biomathématique et d’Estimations Forestières (Labef), University of Abomey-Calavi, Benin Republic, 3Institut Régional de Santé Publique, University of Abomey-Calavi, Benin Republic, 4Public Health Unit, Faculty of Health Science, University of Abomey-Calavi, Benin Republic

&Corresponding author: Damien Barikissou Georgia, University of Abomey-Calavi, Cotonou, Benin. Email: barikiss2000@yahoo.fr

Received: 29 Mar 2025, Accepted: 09 Jul 2025, Published: 06 Aug2025

Domain: Infectious Disease Epidemiology

This is part of the Proceedings of the ECOWAS 2nd Lassa fever International Conference in Abidjan, September 8 – 11, 2025

Keywords: vaccination, compliance, hesitancy, infodemic, COVID-19, Benin 

©Damien Barikissou Georgia et al Journal of Interventional Epidemiology and Public Health (ISSN: 2664-2824). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Damien Barikissou Georgia et al. Factors associated with COVID-19 vaccine compliance and reasons for hesitancy among adults in Benin: A cross-sectional survey.  Journal of Interventional Epidemiology and Public Health. 2025;8(ConfProc5):00273. https://doi.org/10.37432/jieph-confpro5-00273

Introduction

Immunization is one of the most effective public health measures for preventing cases and deaths related to infectious diseases. However, vaccine hesitancy and non-compliance have recently been observed worldwide, particularly in Africa, especially during the COVID-19 emergency. The study aimed to investigate the factors associated with COVID-19 vaccine compliance and reasons for hesitancy in Cotonou, Benin.

Methods

A cross-sectional survey was carried out in Cotonou in December 2022. Respondents were at least 18 years of age. A three-stage stratified random sampling method was used. Vaccination coverage and reasons for hesitancy were assessed. The factors associated with COVID-19 vaccination compliance were identified using a binary logistic regression.

Results

Among the 815 respondents, 53% were vaccinated. The most cited reasons for non-compliance were “fear adverse events” (42.4%), the “rumours” (37.2%), and the “lack of knowledge or confidence in the health system” (10.4%). The COVID-19 vaccination compliance demonstrated spatial heterogeneity with rates increasing from the youngest to the oldest age groups (p=0.0005), from the lowest to the highest education levels (p=0.0021), with a good habit of accessing health care and vaccination, the perception of the risk of contracting the COVID-19 (p=0.0271), and decreased with the fear of adverse effects of the vaccines (p< 0.0001).

Conclusion

The Government and donors should invest in debunking misinformation and disinformation related to all vaccines in Africa to ensure effective routine vaccination and outbreak response.

 
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