Conference Abstract | Volume 8, Abstract NACNDC/19JASH00026 (Poster) | Published:  08 Dec 2025

Retrospective analysis of HIV viral load suppression among patients attending ART clinic at Lira Regional Referral Hospital

Nicholus Sebudde1,2,3,&, Andrew Odur1, Stella Adongo1,4, Ronald Misinde1, Francis Kiweewa1,2

1Lira Regional Referral Hospital, Lira, Uganda, 2Strengthening Institutional Capacity for Research Administration (SICRA), Kampala, Uganda, 3Makerere University, Kampala, Uganda, 4AHF Uganda Cares, Kampala, Uganda

&Corresponding author: Nicholus Sebudde, Lira Regional Referral Hospital, Lira, Uganda, Email: nichimbya@gmail.com / nsebudde@sicra.org

Received: 21 Sep 2025, Accepted: 20 Oct 2025, Published: 08 Dec 2025

Domain: Infectious Disease Epidemiology

This is part of the Proceedings of the National Annual Communicable and Non-Communicable Diseases Conference (NACNDC) and 19th Joint Annual Scientific Health (JASH) Conference 2025

Keywords: HIV viral load suppression, ART outcomes, Lira Regional Referral Hospital

©Nicholus Sebudde et al. Journal of Interventional Epidemiology and Public Health (ISSN: 2664-2824). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Nicholus Sebudde et al. Retrospective analysis of HIV viral load suppression among patients attending ART clinic at Lira Regional Referral Hospital. Journal of Interventional Epidemiology and Public Health. 2025;8(ConfProc6):00026. https://doi.org/10.37432/JIEPH-CONFPRO6-00026

Introduction

Viral load suppression is a key indicator of effective HIV treatment and epidemic control. Despite national efforts, disparities in suppression persist. This study aimed to assess the viral load suppression status and associated demographic and clinical factors among HIV patients attending the ART clinic at Lira Regional Referral Hospital.

Methods

A retrospective analysis was conducted using routinely collected data from ART clinic records covering the period from June 2024 to June 2025. Data on demographic and clinical characteristics, CD4 count, appointment attendance, and viral load outcomes were analyzed. Bivariate and multivariate logistic regression was used to determine factors associated with viral load non-suppression.

Results

Among the reviewed records, the overall viral suppression rate was 95.13%. When stratified by ART regimen, viral suppression was highest among clients on TDF/3TC/DTG (95.9%) compared to other regimens at 88.0%. Factors significantly associated with non-suppression included male gender (AOR: 1.48 [1.17–1.87]), age <18 years (AOR: 2.07 [1.34–3.20]) and >65 years (AOR: 2.36 [1.42–3.91]), CD4 count <200 (AOR: 2.97 [2.24–3.95]), and missed appointments (AOR: 3.06 [2.35–3.99]).

Conclusion

The ART program at Lira Regional Referral Hospital is achieving high levels of viral suppression. However, tailored strategies are needed to improve outcomes among high-risk groups, particularly males, younger and older patients, and those with poor adherence history.

 

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Keywords

  • HIV viral load suppression
  • ART outcomes
  • Lira Regional Referral Hospital
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