Conference Abstract | Volume 8, Abstract ELIC2025263 (Oral 119) | Published: 18 Aug 2025
Ekaete Tobin1,2,3,4,&, Amen Onome Ahabue5, Ola Egbuta3, Martha Okonofua1,3,6, Grace Naregose Okonofua1, Henry Edeko1, Sulymon Saka7, George Akpede7, Danny Akhere Asogun1,2,3
1Institute of Viral and Emergent Pathogens Control and Research, Irrua Specialist Teaching Hospital, Irrua, Nigeria, 2Department of Community Medicine, Ambrose Alli University, Ekpoma, Nigeria, 3Department of Community Medicine, Irrua Specialist Teaching Hospital, Irrua. Nigeria, 4Department of Reform Coordination and Service Improvement, Irrua Specialist Teaching Hospital, Irrua, Nigeria, 5Department of English, Ambrose Alli University, Ekpoma, Nigeria, 6Nursing Services Department, Irrua Specialist Teaching Hospital, Irrua, 7Department of Otolaryngology, Irrua Specialist Teaching Hospital, Irrua, Nigeria
&Corresponding author: Ekaete Tobin, Irrua Specialist Teaching Hospital, Irrua, Nigeria. Email: Ekaete.tobin@gmail.com
Received: 21 May 2025, Accepted: 09 Jul 2025, Published: 18 Aug 2025
Domain: Infectious Disease Epidemiology
Keywords: Lassa fever, Risk Perception, Vaccines, Vaccination Acceptance
©Ekaete Tobin et al. Journal of Interventional Epidemiology and Public Health (ISSN: 2664-2824). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article: Ekaete Tobin et al Perceptions and determinants of acceptance of a future Lassa Fever vaccine in endemic communities of Edo State, Nigeria: A cross-sectional study. Journal of Interventional Epidemiology and Public Health. 2025;8(ConfProc5):00119. https://doi.org/10.37432/JIEPH-CONFPRO5-00119
A cross-sectional study was conducted from May to November 2023 across seven LF hotspot communities, enrolling 790 adults aged over 18 years using multistage sampling. Data were collected using questionnaires adapted from the WHO Behavioural and Social Drivers of Vaccination tool and analysed with SPSS v21. Ethical standards were strictly followed.
A cross-sectional study was conducted from May to November 2023 across seven LF hotspot communities, enrolling 790 adults aged over 18 years using multistage sampling. Data were collected using questionnaires adapted from the WHO Behavioural and Social Drivers of Vaccination tool and analysed with SPSS v21. Ethical standards were strictly followed.
The mean age of participants was 38.0 ± 12.9 years. Over half (52.7%) had a high personal risk perception, and 51.3% were aware of LF vaccine development. Most (93.4%) held positive perceptions towards the future vaccine, and 82.0% expressed their willingness to receive it when it becomes available, though only 27.8% would be willing to pay. Health professionals were the most trusted source of information (70.0%). Past vaccination barriers included late opening times (39.6%) and unavailability of vaccines (27.3%). Concerns regarding the LF vaccine focused on possible side effects (70.6%) and fear of infection from the vaccine itself (72.7%). Willingness to accept the LF vaccine was significantly higher among those with high vaccine perception (AOR = 17.508, p < 0.001), willingness to pay (AOR = 6.445, p < 0.001), high personal risk perception (AOR = 1.945, p = 0.032), and those who knew someone affected by LF (AOR = 4.174, p = 0.004). Conversely, vaccine-hesitant individuals (AOR = 0.293, p < 0.001) and the self-employed (AOR = 0.475, p = 0.037) had significantly lower odds of willingness.
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