Conference Abstract | Volume 9 (ConfPro8): Abstract 52 | Published: 08 Oct 2026
Alex Stéphane Ndjip Ndjock1, &, Michaela Josee Meli2, Nina Ngouenko Nkakoua3, Steve Roland Souga1,4, Prince Théophile Djomou5, Marie-Michelle Ekedy-Lea6, Esther Laura Nyame Dipepa Nwall3
1Department of Public Health, Edea Health District, Littoral Region, Cameroon, 2Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon, 3Regional Technical Group for Malaria Control, Littoral Regional Public Health Delegation, Douala, Cameroon, 4Cameroon Society of Epidemiology (Case), P. O Box 1411 Yaoundé, Cameroon, 5Expanded Programme on Immunisation, Ministry of Health, Yaoundé, Cameroon, 6Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon
&Corresponding author: Alex Stéphane Ndjip Ndjock, Department of Public Health, Edea Health District, Littoral Region, Cameroon, Email: alexndjock@gmail.com
Received: 11 Mar 2026, Accepted: 30 Aug 2026, Published: 08 Oct 2026
Domain: Infectious Disease Epidemiology
Keywords: Malaria vaccine (MV), severe malaria, paediatric malaria, children under five (U5), vaccination coverage, Littoral Region, Cameroon
©Alex Stéphane Ndjip Ndjock et al. Journal of Interventional Epidemiology and Public Health (ISSN: 2664-2824). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cite this article: Alex Stéphane Ndjip Ndjock et al., Preliminary analysis of the impact of malaria vaccine introduction on severe malaria incidence in children under 5 years in the Health Districts of Edea, Japoma and Mbanga, Cameroon (2020-2024). Journal of Interventional Epidemiology and Public Health. 2026;9(ConfPro8):52. https://doi.org/10.37432/JIEPH-CONFPRO8-0052
The malaria vaccine (MV) was introduced in Cameroon in 2024. In its first phase, 42 districts across the 10 health regions were enrolled. Three districts in the Littoral Region are implementing it. This study aims to analyse its early impact on severe malaria cases in children under 5 years of age.
In 2024, a11.2% increase in severe malaria cases was observed compared to 2023, reversing the downward trend seen since 2021. Districts with the lowest vaccination coverage (MV3 at 28.75% and 32.03%) are those where the incidence of severe cases increased most. A significant negative correlation (r = -0.86) was observed between the 3rd dose coverage rate and the variation in severe cases in 2024.
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