Conference Abstract | Volume 9 (ConfPro8): Abstract 64 | Published:  09 Oct 2026

Antiobitic resistance profile of enterobacteriaceae at the Institut national d’hygiene, Togo, January 2020–February 2025

Norbert Kowami Mondjro1,&, Afi Azon2, Adodo Yao Sadji2, Pirenam Kpaikpai2, Koffi Akolly1, Bawoumodon Bidjada2 , Gerard Koglo5, Abravi Kokou1, Lionel Amegan2, Kpatcha Palanga2, Reine Abaya2, Wemboo Afiwa Halatoko2, Rebecca Kinde1,4, Christelle Nikiema1,3, Fifonsi Gbeasor-Komlanvi1, Didier Koumavi Ekouevi1,5

1Centre de Formation et de Recherche en Santé Publique-Université de Lomé, 1Institut National d’Hygiène, 2Division de la Surveillance Intégrée des urgences Sanitaires et de la Riposte, 3African Field Epidemiology Network (AFENET), Togo, 4Centre Africain de Recherche en Épidémiologie et en Santé Publique (CARESP)5

&Corresponding author: Norbert Kowami Mondjro:  Advanced Epidemiologist, WA FELTP, Togo, Email: kwamemondjrofils@gmail.com,    ORCID: https://orcid.org/0009-0000-8102-5290

Received: 11 Mar 2026, Accepted: 30 Aug 2026, Published: 09 Oct 2026

Domain: Infectious Disease Epidemiology

This is part of the Proceedings of the 7th African Epidemiological Association and 1st Ghana Epidemiological Society Conference, 13 – 15 October, 2026

Keywords: Public health, INH, antimicrobial, resistance, Togo

©Norbert Kowami Mondjro et al. Journal of Interventional Epidemiology and Public Health (ISSN: 2664-2824). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this article: Norbert Kowami Mondjro et al., Antiobitic resistance profile of enterobacteriaceae at the Institut national d’hygiene, Togo, January 2020–February 2025. Journal of Interventional Epidemiology and Public Health. 2026;9(ConfPro8):64. https://doi.org/10.37432/JIEPH-CONFPRO8-0064

Introduction

Antimicrobial resistance constitutes a silent, unreported pandemic that undermines the effectiveness of antibiotic therapy. This study aims to determine the antibiotic susceptibility profile of Enterobacteriaceae to help update treatment protocols.

Methods

This was a descriptive cross-sectional study of antibiotic susceptibility test reports for Enterobacteriaceae strains isolated from biological samples at the INH bacteriology laboratory from January 2020 to February 2025. Using R software, resistance rates were estimated with a 95% confidence interval (95% CI).

Results

A total of 22,960 samples were analyzed at the bacteriology laboratory. Urine and pus samples were predominant, accounting for 75.04% and 16.5% of the total, respectively. Cultures were positive for 3,198 samples, including 2,128 Gram-negative bacterial strains and 1,070 Gram-positive bacterial strains. Enterobacteriaceae (66.5%). Escherichia coli was resistant to piperacillin at rates of 85.36%, 82.5%, 66.67%, 68.0%, and 100%, respectively, from 2020 to 2024. This represents an acquired resistance rate of 14.36%. Trimethoprim/sulfamethoxazole resistance was 80.95% and 87.96% in 2020 and 2024, respectively; norfloxacin resistance increased by 13.14% between 2020 and 2024. Klebsiella pneumoniae was resistant to ciprofloxacin at 35.7% in 2020 and 40.6% in 2024, and to ofloxacin at 39.2% in 2020 and 40.75% in 2024. Only cefoxitin (90.38%) and imipenem (98.6%) still retain activity against the isolated Enterobacteriaceae strains. The production of penicillinases and extended-spectrum beta-lactamases (ESBL), was observed in 91.31%, and  74.93% of Enterobacteriaceae strains, respectively.

Conclusion

The phenomenon of antibiotic resistance is real, with only a small proportion of Enterobacteriaceae strains isolated still susceptible to antibiotics. Extending this study to several healthcare facilities in Togo and communicating with infectious disease specialists are essential to help adapt treatment protocols for infections.

 
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